General Hospital’s Cheating Doctors, From Alan and Monica to Patrick and Griffin

The show's first cheating doc was Dr. Phil Brewer (Roy Thinnes), who stepped out on his wife, long-suffering nurse Jessie Brewer (Emily McLaughlin). In 1963, his flirtation with schoolteacher Cynthia Allison, who was engaged to Phil and Jessie's colleague Dr. Ken Martin, crossed the line into a hot and heavy affair. Cynthia dumped Ken to be with Phil, and Jessie was heartbroken when Phil told her he was in love with Cynthia. She filed for divorce and kept mum to Phil that she was pregnant with their child, but when he found out, he called things off with his mistress and tried to make his marriage work. Alas, Jessie miscarried the baby in 1964.

Fellow physicians Jeff Webber (Leslie Charleson) and Monica Bard's marriage was sinking fast in 1976. Monica was in love with Jeff's brother, Rick Webber, to whom she had once been engaged, a fact she could no longer deny when Rick returned from the dead. Soon, he and Monica had fallen back into bed. Meanwhile, Heather Grant (Mary O'Brien) had the hots for Jeff and dreamed of becoming a doctor's wife. They, too, began sleeping together, and soon, Heather found herself pregnant. In 1977, she gave birth to Jeff's son, Steven Lars, and after Monica and Jeff's divorce was finalized, she was briefly married to Jeff herself.

When Dr. Rick Webber (Chris Robinson) tied the knot with Dr. Lesley Williams in 1977, he felt confident that he'd gotten Monica (Leslie Charleson) out of his system for good. But in 1979, the year after she tied the knot with Dr. Alan Quartermaine, a series of events stirred up Rick and Monica's feelings for one another. Before long, they were back in bed together. They planned to leave their spouses and Monica did, indeed, separate from Alan, but after Lesley's daughter Laura (who Rick had adopted) was nearly killed in an accident, he decided to make his marriage work. It was then that Monica discovered she was pregnant! Monica believed that Rick was the father, and when Lesley was forced to deliver her baby during a terrible snowstorm, a delirious Monica blurted this out to Rick's stunned wife! In 1980, Rick longed to claim Monica's son (Alan, Jr., aka AJ) as his own and the pair began seeing one another again. Alan played dumb, but knew Monica was unfaithful and plotted to kill both her and Rick. In the end, a blood test proved that AJ was Alan's biological son and Alan and Monica found their way back together, as did Rick and Lesley.

Dr. Alan Quartermaine (Stuart Damon) had many mistresses over the course of his marriage(s) to Monica, no paragon of faithfulness herself. But perhaps Alan's most consequential affair was with Susan Moore (Gail Ramsey), who, in 1982, ended up bearing him a son, Jason (well, two sons, but Alan died before he knew that Jason had a twin, Drew).

Dr. Noah Drake and Nurse Bobbie Spencer were hot and heavy when they first hooked up in 1981. But Noah was loath to commit, and after Bobbie faked blindness to test her beau's feelings for her, he broke things off. Bobbie was crushed and left town for a while, during which time Noah began a romance with Tiffany Hill. When Bobbie returned to Port Charles several months later, Noah tried to fight his attraction to her, but early in 1983, they hit the sheets. Noah was wracked with guilt over betraying Tiff and she was heartbroken when, on the night she thought he was going to propose, he instead told her he wanted to see other women. Noah soon regretted his decision and begged Tiff for another chance but she turned him down, and he decided to move away.

Dr. Monica Quartermaine took many outside lovers during her years as Mrs. Alan Quartermaine, including two fellow doctors — her previously mentioned ex, Dr. Rick Webber, and Dr. Pierce Dorman, who wound up suing her for sexual harassment. In terms of awkward family dynamics, though, nothing could top her 1988 roll in the hay (literally and figuratively!) with a man she knew as tennis pro Ward ... who turned out to actually be Alan's nephew, Ned Ashton (then-Kurt Robin McKinney)! That secret became particularly sticky when Ned fell in love with Monica's surprise daughter, Dawn.

In 1989, Dr. Simone Ravelle Hardy (Laura Carrington) and her hubby, Dr. Tom Hardy, hit a rough patch in their marriage and decided to separate. She fell into bed with fellow doctor Harrison Davis — but the very next day, she and Tom reconciled and made love. When Simone soon found out she was expecting, she wasn't sure who the father was. She hid her tryst with Harrison from Tom until after her son, Tommy Hardy, was born. A paternity test indicated that Harrison was the daddy, and Tom and Simone fought him for custody of Tommy. It then came out that the paternity test had been tampered with by Simone's mother, and Tom was the true biological father. Still, Tom and Simone landed in divorce court.

Dr. Tony Jones's (Brad Maule) marriage to Nurse Bobbie Jones was in shambles after Bobbie was tempted by Damian Smith and the couple's young daughter, BJ Jones, was killed in a school bus accident in 1995. In 1996, this made him easy prey for Bobbie's secret daughter, Carly (then-Sarah Brown). His affair with Carly led to a divorce from Bobbie and a near marriage to a pregnant Carly — but it turned out that the baby she was carrying, Michael, was not actually his; she had gotten pregnant via a one-night stand with AJ Quartermaine.

In 2010, Dr. Patrick Drake (Jason Thompson) and his wife, Dr. Robin Scorpio-Drake, had busy lives as medical professionals and parents to a young daughter, Emma. Patrick (Noah Drake's' son, who had followed in his ladies' man footsteps) was chafing a bit under the confines of domestic life, and he felt neglected by Robin's devotion to her work. Enter Dr. Lisa Niles (Brianna Brown), a surgeon and Patrick's college girlfriend. Her reminders of his freewheeling bachelor days proved irresistible to Patrick, and one night, they shared a kiss that escalated into sex in his office. Patrick was filled with remorse and concealed his infidelity from Robin, but ultimately confessed to a shocked Robin, who threw him out of the house. Lisa's obsession with Patrick soon reached dangerous levels. She stalked the couple and in 2011, kidnapped Robin. Patrick rescued her, but Lisa was far from done. She deliberately infected herself with a blood sample from Robin, who was HIV-positive, to try to frame Robin for attempted murder. Her plot failed and after attempting to infect Patrick with Robin's blood, her reign of terror was finally brought to an end by Patrick's half brother, Matt Hunter, who went to jail for causing her demise.

Dr. Griffin Munro (Matt Cohen) was in a relationship with Ava Jerome (Maura West, r.) when, in 2018, the two had a big blow-up the night of the Nurses' Ball after she angrily accused him of having a thing for her daughter, Kiki (Hayley Erin). Griffin adamantly denied it and was genuinely crushed when Ava appeared to end things between them. He and Kiki drowned their sorrows together and one thing led to another (which is to say, to the bedroom!). Kiki was forced to hide when her mom showed up at Griffin's the next morning to apologize for her outburst and to try to patch things up with Griffin. He wanted to come clean right away, but Kiki texted him from the other room to tell him not to. Griffin remained silent and tried to make a go of things with Ava even as thoughts of Kiki danced in his head. It was during the trial when Kiki sued Dr. Bensch for sexual harassment that the truth about Kiki and Griffin's night together came to Ava's attention when Franco accidentally texted her about it and not his father, Scott (Kiki's attorney). Griffin ultimately had to confess to the tryst on the stand, earning him multiple slaps from Ava. Ava was unimpressed when he used the "We were on a break!" excuse, snapping at him, "During this 12-hour break-up did you have to jump into bed with my daughter?!"